Red & Infrared 630nm LED PBM for Subcutaneous Fat in Obese Individuals

July 28, 2025 Red Arrow

Study Overview

Description: This controlled comparative intervention study aimed to evaluate the effects of photobiomodulation therapy (PBMT) using Light Emitting Diodes (LED) associating red (630 nm) and infrared (850 nm) wavelengths on subcutaneous fatty tissue of obese individuals.
Source: PubMed

Summary

Participants: Women with grade II obesity. (A specific number of participants is not provided in the abstract, but it's a "sample").
Intervention: LED PBMT with associated red (630 nm) and infrared (850 nm) wavelengths applied sequentially on the left side of the abdomen. The right side served as a control.
Methods: Subcutaneous fatty tissue samples were collected at the time of bariatric surgery for histological and immunohistochemical evaluation using markers like Caspase 3, Cleaved Caspase 3, CD68+ (macrophages), HSL, and adipophilin.
Conclusion: PBMT combining red and infrared LEDs promoted autophagic lipolysis induced by adipocyte cell apoptosis in the subcutaneous tissue of obese individuals. Participants showed significant positivity in the expression of apoptosis and lipid metabolism markers in the intervention sample compared to the control.